Estimating the proportion of neutral mutations
نویسندگان
چکیده
منابع مشابه
Estimating the Proportion of True Null Hypotheses under Dependence
Multiple testing procedures, such as the False Discovery Rate control, often rely on estimating the proportion of true null hypotheses. This proportion is directly related to the minimum of the density of the p-value distribution. We propose a new estimator for the minimum of a density that is based on constrained multinomial likelihood functions. The proposed method involves partitioning the s...
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We have previously shown that computer simulations of processes that generate selectively advantageous changes together with random duplications and deletions give rise to genomes with many different genes embedded in a large amount of dispensable DNA sequence. We now explore the consequences of neutral changes on the evolution of genomes. We follow the consequences of sequence divergences that...
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ژورنال
عنوان ژورنال: New Zealand Journal of Botany
سال: 1993
ISSN: 0028-825X,1175-8643
DOI: 10.1080/0028825x.1993.10419507